Carboplatin monotherapy
WebJun 19, 2024 · Detailed Description: This is a Phase 1/2, open-label, prospective, multi-center, single-arm study to establish the safety and feasibility of blood-brain-barrier … WebRe-treatment with single-agent platinum has long been considered standard therapy for patients with platinum-sensitive disease, and, based on its favorable therapeutic profile, carboplatin has become the treatment agent of choice. High response rates are seen with platinum agents used in combination with paclitaxel or gemcitabine.
Carboplatin monotherapy
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WebJul 30, 2024 · This trial will use olaparib or carboplatin as initial therapy with crossover to the alternate or second-line drug after first progression for patients with tumors containing BARD1, BRCA1, BRCA2, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, or RAD54L inactivating mutations. WebCarboplatin is usually given by infusion into a vein (intravenous, IV). Carboplatin can also be given intra-peritoneal, directly into the peritoneal cavity in the abdomen. The amount …
Web1 day ago · In KEYNOTE-407, when KEYTRUDA was administered with carboplatin and either paclitaxel or paclitaxel protein-bound in metastatic squamous NSCLC, KEYTRUDA was discontinued due to adverse reactions in 15% of 101 patients. ... In KEYNOTE-048, KEYTRUDA monotherapy was discontinued due to adverse events in 12% of 300 … WebJan 11, 2024 · Day 1: Cabazitaxel 25mg/m 2 IV over 60 minutes (for healthy men who wish to be more aggressive) Days 1-21: Prednisone 10mg orally once daily. Repeat cycle every 3 weeks. Docetaxel rechallenge ...
WebJun 14, 2011 · Major Finding: Among patients with metastatic triple-negative breast cancers, single-agent therapy with cisplatin or carboplatin produced an overall response rate of 30.2%.Data Source: Multicenter prospective phase II trial by the Translational Breast Cancer Research Consortium.Disclosures: The stud WebAug 29, 2024 · Study Description Go to Brief Summary: The investigators propose a phase II study to evaluate the efficacy of carboplatin monotherapy in the tumor subgroup of metastatic castration-resistant prostatic carcinomas with somatic abnormality in the Homologous Recombination (HR) pathway.
WebJun 1, 2024 · This randomized clinical trial shows that compared with every-3-weeks or weekly carboplatin-paclitaxel regimens, single-agent carboplatin was less active with …
WebCarboplatin, Letrozole, Paclitaxel Description This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. free mapping with pinsWebSep 14, 2024 · Since many patients begin chemotherapy with such a combination, and since platinum agents such as carboplatin tend to cause significant problems with bone … free map pinpoint creatorWebA Phase 1b/2, Protocol Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Sotorasib Monotherapy and in Combination With Other Anti-cancer Therapies in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101) Secondary IDs: Study Status ... Experimental: Sotorasib + carboplatin, pemetrexed, docetaxel ... free mapping software routingWebThe treatment arms involved included TKI monotherapy (abbreviated as TKI), TKI plus pemetrexed (TKIplusP), TKI plus pemetrexed and carboplatin (TKIplusPC), TKI plus bevacizumab (TKIplusBev), TKI plus ramucirumab (TKIplusRam), TKI plus apatinib (TKIplusApa), TKI plus cryoablation (TKIplusCAb), TKI plus microwave ablation … free mapping software for sales territoriesWebOct 21, 2024 · INTRODUCTION The following material represents a subset of chemotherapy and immunotherapy regimens that are used for the treatment of women with gynecologic cancers. This is not an exhaustive list; it includes regimens that are considered by the authors and editors to be commonly used and important for the care of patients … free map practice tests kindergartenWebApr 27, 2024 · Carboplatin–Paclitaxel Recommended For Elderly Advanced Ovarian Cancer Patients. medwireNews: Findings from the Elderly Women With Ovarian Cancer … free map pinning united statesWebJan 2, 1998 · Carboplatin (Paraplatin), a derivative of cisplatin, has far less nonhematologic toxicity, although myelosuppression may be slightly greater than that observed with … free map presentation software