WebTo assess the prognostic value of STAT1, PD-1, and PD-L1 expression in ovarian cancer, we performed bioinformatics analysis. A high level of STAT1 expression was associated with better overall survival (OS) in 2 studies (n = 248 cases) and progress-free survival (PFS) in 3 studies (n = 982 cases) (Supplementary Figure S2). WebMay 8, 2024 · The tumor-suppressive role of STAT1 is driven by findings that the reconstitution of STAT1 in STAT1-deficient murine fibrosarcoma cells significantly suppressed tumorigenicity and metastasis in nude mice. 53 The high expression of STAT1 is reported to have a good prognosis compared with the low or negative expression of …
STAT1 as a potential prognosis marker for poor outcomes of early …
WebFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that lanes 1‑3 of the EMSA results shown in Fig. 6 on p. 1278 were strikingly similar to data that had already appeared in a different form in the following publication by different authors at diffe … WebNotably, the STAT1, STAT2, and IRF9genes are all ISGs that are strongly induced by type I IFNs. Although the expression of most ISGs is mediated by this canonical signaling pathway, the components of the pathway have additional, noncanonical functions (4). ctv schedule tv
Targeting STAT3 in Cancer Immunotherapy - Molecular Cancer
WebWe, the Editors and Publisher of the journal Cell Cycle, have retracted the following article:. Yuguang Yang, Jin Wu, Hongfeng Zhou, Wenming Liu, Jincai Wang and Qingyuan Zhang. STAT1-induced upregulation of lncRNA LINC01123 predicts poor prognosis and promotes the progression of endometrial cancer through miR-516b/KIF4A. WebApr 10, 2024 · Abstract. Proteomic analyses indicate that STAT1 protein (signal transducer and activator of transcription 1 or transcription factor ISGF-3 components p91/p84) is … WebFeb 2, 2013 · MUC1-C activates STAT1/3 in an auto-inductive loop. Signal transducer and activator of transcription (STAT) family members have been implicated in the link between inflammation and cancer . STAT1 is activated in the inflammatory response to interferons and is constitutively upregulated in breast and other carcinomas . ct vs ch studs